Sciphar Hi-tech Industry

Natural active ingredients and intermediates   

Product name: Sanguinarine

Plant source: Macleaya cordata

Molecular formula: C20H14NO4

Molecular weight: 332.335

Construction:

CAS No: 2447-54-3

Appearance: light red fine powder, soluble in water

Specifications: 50%,98% HPLC

Application: Feed antibiotics, Feed additives, harmaceuticalchelerythrine.

Functions:
1) Sanguinarine has been show to be reversible inhibitors of the enzymatic hydrolysis of acetylthiocholine.
2) Sanguinarine ( pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation.
3) It was reported that a study was made of a possible inhibitory action on the enzymatic hydrolysis of acetylthiocholine by human erythrocyte acetylcholinesterase of principal alkaloids isolated from Chelidonium majus L. And Macleaya cordata and microcarpa, and of drugs Ukrain and Sanguirythrine. Among all examined agents berberine, sanguinarine and Sanguirythrine were the strongest inhibitors of this reaction. Judging from the data obtained, sanguinarine and chelerythrine exert similar inhibitory effects on the reaction of enzymatic hydrolysis of acetylthiocholine.

Packing: 1kg/ aluminum bag
25kgs/ fiber durm or according to customer's demand

Shelf life: 2 years

 

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